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Testosterone and Hair Loss: Understanding the Connection

Jan 8, 2024
2 min read

Updated: 3 days ago


Hair Loss St. Louis
Hair Loss St. Louis

Scalp hair loss alone does not tell you whether testosterone is high or low. Pattern hair loss reflects inherited follicle susceptibility and other biological factors. Women and men can also lose hair for reasons unrelated to androgen levels.


What does DHT do?


The enzyme 5-alpha-reductase converts testosterone to dihydrotestosterone, or DHT. In susceptible scalp follicles, androgen signaling contributes to gradual miniaturization. A person can develop pattern hair loss with hormone levels in the usual range.


Does hair loss mean I need testosterone?


No. The Endocrine Society guideline recommends diagnosing male hypogonadism using compatible symptoms and consistently low testosterone measurements, with evaluation of the cause. Scalp thinning by itself is not enough to establish that diagnosis. Testosterone treatment is not a routine hair-regrowth treatment.


Androgen treatment may contribute to progression in someone susceptible to pattern hair loss. Discuss new shedding or thinning with the prescribing clinician and a dermatologist; do not stop prescribed treatment on your own. Prescription testosterone and over-the-counter “testosterone boosters” are different products.


What about hair loss in women?


Female pattern hair loss has complex causes, and many affected women do not have elevated androgens. Symptoms such as irregular menstrual periods or new facial hair may guide an evaluation. The evidence should not be simplified to a claim that all female hair loss is caused by DHT.


Treat the diagnosis


For male pattern hair loss, randomized trials support finasteride in appropriately selected men. It requires discussion of adverse effects and reproductive precautions. It is not a medication everyone taking testosterone should automatically receive.


Topical minoxidil is another established option for pattern hair loss. A randomized trial in women compared 5% foam once daily with 2% solution twice daily over 24 weeks. Choice of formulation and treatment depends on the individual.


Oral minoxidil is used off label for hair loss and requires a clinician’s assessment of cardiovascular risks and other adverse effects. Its use should not be presented as interchangeable with topical minoxidil.


PRP may improve density in some people with pattern hair loss, but research methods and results vary. A 2024 systematic review highlighted important limitations in the trials. Evidence for pattern hair loss does not establish benefit for every cause of shedding.


Supplements and next steps


Biotin and other supplements should not be promised to prevent androgen-related hair loss. Treat a nutritional deficiency when indicated, rather than assuming that extra vitamins will help. Bring your medication and supplement list to an appointment so the likely cause can be assessed.



How to get started with hair loss treatment today

At Mid-County Dermatology, our dermatologists evaluate hair loss and discuss treatment options based on the cause, potential benefits, and risks. Results vary by diagnosis and treatment. Learn more about our hair-loss care. Schedule online or call (314) 994-0200 to arrange an appointment.

 

This article is for general educational purposes only and is not medical advice. If you have questions or concerns about your skin, talk with one of our dermatologists at Mid-County Dermatology.


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